Project MaVen aims to manufacture replacement ventricles to treat heart disease.
Supported by the Government of Canada’s New Frontiers in Research Fund, MaVen brings together 22 Principal Investigators from 10 different institutions. A highly interdisciplinary approach is our key to making a big impact in high-risk, high-reward areas of research.
MaVen Research Pillars
Stem Cell Science
We are generating heart cells and blood vessels from stem cells in the quantities needed for therapeutic applications.
Synthetic Biology
We are engineering stem cells for heart muscle that beat stronger and survive longer when blood supplies are interrupted.
Computational Modeling
Our in silico models predict electrical signalling and dynamic blood flow in engineered tissue structures.
3D Bioprinting
With advanced 3D bioprinting strategies, we are using stem cells and biomaterials to print functional ventricular chambers of the heart.
Translation
Our team’s ethicists, psychologists, and clinicians are building frameworks to determine clinical readiness of our novel therapies.